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Any substance capable of stimulating an immune response is called an antigen (抗原). Antigens are not to be confused with allergens (过敏原)，which are most often harmless substances that provoke the immune system to set off the inappropriate and harmful response known as allergy. An antigen can be a virus, a bacterium, or even a portion or product of one of these organisms. Tissues or cells from another individual (except an identical win, whose cells carry identical self makers act as antigens; because the immune system recognizes transplanted tissues as foreign, it rejects them. The body will even reject nourishing proteins unless they are first broken down by the digestive system into their primary, nonantigenic building blocks. An antigen announces its foreignness by means of intricate and characteristic shapes called epitopes (抗原表位), which protrude (突出) from its surface. Most antigens, even the simplest microbes, carry several different kinds of epitomes on their surface, some may even carry several hundred. Some epitomes will be more effective than others at stimulating an immune response. Only in abnormal situations does the immune system wrongly identify self as nonself and execute a misdirected immune attack.
36 What is used to describe the communication network consisting of cells in the immune system?
A The immune system's memory.
B Bees flying around a hive.
C Immune troops eliminating intruders.
D A sea of microbes.
37 The immune cells and other cells in the body coexist peaceably in a state known as
A balance.
B harmony.
C tolerance.
D self-tolerance.
38 How do the immune cells recognize an antigen as "foreign" or "nonself"?
A Through characteristic shapes on the antigen surface.
B Through an allergic response.
C Through blood type.
D Through fine hairs protruding from the antigen surface.
39 Which of the following statements is true?
A Allergens are usually harmful substances.
B Antigens can trigger an immune response.
C People with antigens do not suffer from obvious responses.
D There is no difference between an antigen and an allergen.
40 Which of the following best expresses the main idea of this passage?
A The basic function of the immune system is to distinguish between self and nonself.
B An antigen is any substance that triggers an immune response.
C One of the immune system's primary functions is the allergic response.
D The human body is an appropriate habitat for microbes.
第三篇 Be Alert to Antimicrobial（抗微生物的）Resistance
The ability of micro-organisms to find ways to evade the action of the drugs used to cure the infections they cause is increasingly recognized as a global public health issue. Some bacteria have developed mechanisms which make them resistant to many of the antibiotics (抗生素) normally used for their treatment (multi-drug resistant bacteria), so pose particular difficulties, as there may be few or no alternative options for therapy. They constitute a growing and global public health problem. WHO suggests that countries should be prepared to implement hospital infection control measures to limit the spread of multi-drug resistant strains (菌株) and to reinforce national policy on prudent use of antibiotics, reducing the generation of antibiotic resistant bacteria.
An article published in 7"he Lancet Infectious Diseases on 11 August 2010 identified a new gene that enables some types of bacteria to be highly resistant to almost/all antibiotics. The article has drawn attention to the issue of AMR3 (antimicrobial resistance), and, in particular, has raised awareness of infections caused by multi-drug resistant bacteria.
While multi-drug resistant bacteria are not new and will continue to appear, this development requires monitoring and further study to understand the extent and modes of transmission, and to define the most effective measures for control.
Those called upon to be alert to the problem of antimicrobial resistance and take appropriate action include consumers, managers of hospitals, patients, as well as national governments, the pharmaceutical (制药的) industry, and international agencies.
WHO strongly recommends that governments focus control and prevention efforts in the following areas like surveillance for antimicrobial resistance; rational antibiotic use, including education of healthcare workers and the public in the appropriate use of antibiotics; introducing or enforcing legislation related to stopping the selling of antibiotics without prescription; and strict adherence to infection prevention and control measures, including the use of hand-washing measures, particularly in healthcare facilities.
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